Research | Kevin Cook

My research focuses on merging neuroimaging methods with fundamental cognitive neuroscience principles to better understand the neurodiversity of children with and without neurodevelopmental disorders. Through fostering a better understanding of early life influences during the fetal and perinatal period contributing to neurodiversity, my hope is that we can better understand and help children who are experiencing significant distress and impairment in their daily lives.

Papers

Christoffel K., De Asis-Cruz J., Govindan R.B., Kim J-H, Cook K.M., Kapse K., Andescavage N., Basu S., Spoehr E., Limperopoulos C., Du Plessis A. (2024). Central Autonomic Network and heart rate variability in premature neonates. Dev Neurosci. 6. https://doi.org/10.1159/000536513

Cook K.M., De Asis-Cruz J., Kim J-H, Basu S.K., Andescavage N., Murnick J., Spoehr E., Liggett M., du Plessis A.J., Limperopoulos C. (2023). Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits. BMC Med. 1 (435). https://doi.org/10.1186/s12916-023-03141-w

Cook K.M., De Asis-Cruz J., Basu S.K., Andescavage N., Murnick J., Spoehr E., du Plessis A.J., Limperopoulos C. (2023). Ex-utero third trimester developmental changes in functional brain network organization in infants born very and extremely preterm. Front Neurosci. 17. https://doi.org/10.3389/fnins.2023.1214080

Cook K. M., Asis-Cruz J. D., Lopez C., Quistorff J., Kapse K., Andersen N., Vezina G., Limperopoulos C. (2023). Robust sex differences in functional brain connectivity are present in utero. Cerebral Cortex. 33 (6) https://doi.org/10.1093/cercor/bhac218

Kim J-H., Asis-Cruz J. D., Cook K. M., Limperopoulos, C. (2023). Gestational age-related changes in the fetal functional connectome: in utero evidence for the global signal. Cerebral Cortex. 33 (5). https://doi.org/10.1093/cercor/bhac209

Asis-Cruz J. D., Krishnamurthy D., Jose C., Cook K. M., Limperopoulos C. (2022). FetalGAN: Automated Segmentation of Fetal Functional Brain MRI using Deep Generative Adversarial Learning and Multi-Scale 3D U-Net. Frontiers in Neuroscience. 16. https://doi.org/10.3389/fnins.2022.887634

Cook K.M., You X., Cherry C.B.J, Merchant J.M., Skapek, M., Powers, M., Pugliese C.E., Kenworthy L., Vaidya C.J. (2021). Neural correlates of schema-dependent episodic memory and association with behavioral flexibility in autism spectrum disorders and typical development. Journal of Neurodevelopmental Disorders.13 (35). https://doi.org/10.1186/s11689-021-09388-9

Rye, M. S.; Fleri, A. M.; Moore, C. D.; Worthington, E. L.; Wade N. G.; Sadage, S. J.; Cook, K. M. (2012). Evaluation of an intervention designed to help divorced parents forgive their ex-spouse. Journal of Divorce and Remarriage, 53, 231-245. https://doi.org/10.1080/10502556.2012.663275

Moore, C. & Cook, K. M. (2011). Promoting and Measuring Family Caregiver Self-Efficacy in Caregiver-Physician Interactions. Social Work in Health Care, 50, 801-814. https://doi.org/10.1080/00981389.2011.580835

Selected Conference Platforms and Posters

Cook K.M., Asis-Cruz J.D., Kim J.H., Spoehr E., Myers M., Basu S.K., Andescavage N., du Plessis A., Limperopoulos C. (2023, May). Preterm Pain in the NICU Is Associated with Atypical Functional Brain Connectivity and Developmental Deficits at 18-Months. Platform presentation at the 2023 Pediatric Academic Societies Meeting, Washington, DC

Damera S.R., Asis-Cruz J.D., Cook K.M., Kapse K.J., Spoehr E., Basu S.K., Andescavage N., Limperopoulos C. (2023, May). Regional Homogeneity as a Marker of Sensory Cortex Dysmaturity in Premature Infants Platform presentation at the 2023 Pediatric Academic Societies Meeting, Washington, DC

Cook K.M., De Asis-Cruz J., Sitrin C., Barnett S., Krishnamurthy D., Kapse K., Andescavage N., Quistorff J., Lopez C., Limperopoulos C. (2022, April). Relative neighborhood disadvantage is associated with increased functional network segregation in fetal brains. Platform Talk at the 2022 Pediatric Academic Societies Meeting, Denver, CO

Cook K.M., De Asis-Cruz J., Kim J.H., Kapse K., Andescavage N., Basu S., Kapse K., du Plessis A., Limperopoulos C. (2022, April). Early exposure to the extra-uterine environment in premature infants is associated with altered functional brain connectivity compared to in-utero age-matched fetuses. Platform Talk at the 2022 Pediatric Academic Societies Meeting, Denver, CO

Cook K.M., De Asis-Cruz J., Lopez C., Quistorff J., Kapse K., Andresen A., Vezina G., Limperopoulos C. (2021, May). In utero MRI differentiates male and female human fetal brain functional connectivity. Platform Talk at the 2021 Pediatric Association Society Meeting, Virtual

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Pugliese C.E., Kenworthy L., Vaidya C.J. (2020, May). Neural corelates of schema-dependent encoding in children with autism spectrum disorders: The role of behavioral flexibility. Poster presented at the 2020 Cognitive Neuroscience Society meeting, Boston, MA.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Pugliese C.E., Kenworthy L., Vaidya C.J. (2020, April). Children with autism spectrum disorder do not engage brain regions responsible for flexible thought in the same manner as typically developing children. Platform Talk at the 2020 Association for Clinical and Translational Science, Washington, DC.

Brocke, S., Cook, K., Rabany, L., Corbera, S., Pelphrey, K., Bell, M., & Assaf, M. (2016, May). Investigating Symptom Overlap Between Individuals with High-Functioning Autism Spectrum Disorder and Schizophrenia. Poster presented at the 2016 International Meeting For Autism Research, Baltimore, MD.

Brocke, S, Cook, K., Winters, C., Corbera, S., Pearlson, G., Pelphrey, K., Bell, M., & Assaf, M. (2015, May). Characterizing social cognitive deficits in high-functioning autism spectrum disorders and schizophrenia. Poster presented at the 2015 International Meeting For Autism Research, Salt Lake City, UT.

Complete List of Conference Platforms and Posters

Cook K.M., De Asis-Cruz J., Kim, J.H., Andescavage, N., Basu S.K., du Plessis, A.J., Limperopoulos C. (2021, November). Functional connectivity at term equivalent age predicts frequency of neonatal intensive care unit procedures in infants born very preterm using machine learning. Poster presented at the 2021 Society for Neuroscience meeting. Chicago, IL.

Cook K.M.*, Stern, C.*, De Asis-Cruz, J., Barnet S.D., Krishnamurthy, D., Limperopoulos C. (2021, November). Maternal education is associated with functional segregation of the fetal connectome. Poster presented at the 2021 Society for Neuroscience meeting. Chicago, IL. *Co-first authors

Cook K.M., You X., Vaidya C.J. (2021, May). Atypical Hippocampal Network Connectivity Implicating Social, Executive, Attention, and Memory Function in Autism Spectrum Disorder. Poster presented at the 2021 International Society for Autism Research meeting, Virtual.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Pugliese C.E, Kenworthy L., Vaidya C.J. (2020, May). Neural corelates of schema-dependent encoding in children with autism spectrum disorders: The role of behavioral flexibility. Poster presented at the 2020 Cognitive Neuroscience Society meeting, Boston, MA.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Kenworthy L., Vaidya C.J. (2020, May). Neural corelates of schema-dependent encoding in children with autism spectrum disorders: The role of behavioral flexibility. Poster accepted for the 2020 International Society for Autism Research, Seattle, WA.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Kenworthy L., Vaidya C.J. (2020, April). Children with autism spectrum disorder do not engage brain regions responsible for flexible thought in the same manner as typically developing children. Platform Talk at the 2020 Association for Clinical and Translational Science, Washington, DC.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Pugliese C.E, Kenworthy L., Vaidya C.J. (2019, October). Differing patterns of activation for schema memory in autism spectrum disorder. Poster presented at the 2019 Georgetown University Medical Center Student Research Day, Washington, DC.

Cook K.M., Cherry C.B.J, Merchant J.M., You X., Skapek, M., Powers, M., Kenworthy L., Vaidya C.J. (2019, April). Pre-existing knowledge and autism spectrum disorder: Differences in brain activation for a schema driven subsequent memory task. Poster presented at the 2019 Association for Clinical and Translational Science, Washington, DC.

Corbera, S., Cook, K., Brocke, S., Dunn, S., Wexler, B., & Assaf, M. (2014, May). The relationship between functional deficits and empathy for emotional pain in schizophrenia. Poster presented at the 69th Annual Meeting of the Society of Biological Psychiatry, New York, NY.

Corbera, S., Cook, K., Brocke, S., Dunn, S., Assaf, M., & Wexler, B. (2014, April). Empathy to emotional pain in schizophrenia. Poster presented at the 21st Annual Meeting of the Cognitive Neuroscience Society, Boston, MA.

Farrell, J. E.; Rye, M. S.; Cook, K. M.; & Woofield, M. (2011, August). Forgiveness, mood, and attachment style. Poster presented at the 119th Annual Meeting of the American Psychological Association, Washington DC.

Lanham, M. E.; Rye, M. S.; Fleri, A. M.; Cook, K. M.; Shaikh, S. & Krasner, S. (2010, August). The relationship between gratitude, burnout, and job satisfaction. Poster presented at the 118th Annual Meeting of the American Psychological Association, San Diego, CA.